aHUS 2024
Data collection
Kidney transplantation in patients with complement-mediated/atypical hemolytic uremic syndrome (aHUS): management, outcome and risk of recurrence
New project ideas?
If you have an idea for a research topic and want to make use of the CERTAIN registry data, do not hesitate to contact us or provide us directly with a well elaborated analysis plan. Below you will find a template for an analysis plan and technical requirements.
Ongoing research projects
Interested into the running project and where you can contribute? Contact the appropriate study coordinator listed below or the CERTAIN registry HQ.
AIRTrain
Recruitment
Artificial Intelligence and Biomarkers after Pediatric Renal Transplantation: Innovative Tailoring of Immunosuppression
COVID-19
Data collection
European study on the risks of SARS-COV-2 infection in pediatric kidney transplant recipient
EuPAKT
Recruitment
Prospective longitudinal multi-center study evaluating modifiable barriers to accessing transplantation and transplant outcomes in children, in Europe. Short title: European Paediatric Access to Kidney Transplantation
Hypertension 2020
Data collection
Arterial hypertension and cardiovascular comorbidity after renal transplantation – triggers, treatment and sequelae.
PTH 2019
Data collection
Hyperparathyroidism after paediatric renal transplantation: risk factors, management strategies and association with longitudinal growth
SRNS 2019
Data collection
Recurrence of nephrotic syndrome after pediatric kidney transplantation in Europe: risk factors, treatment and outcome
Research projects under analysis
Interested into the projects where the database is already closed? Contact the appropriate study coordinator listed below or the CERTAIN registry HQ.
DGF Outcome
Analysis
The impact of delayed graft function on rejection and long-term outcome in paediatric kidney transplant recipients - a multicentre matched case-control study
Failing allografts
Analysis
Current practices in managing children and young people with failing grafts
HPVaxResponse
Analysis
Prevention of human papillomavirus (HPV) infection in paediatric kidney and liver transplant recipients and in paediatric patients with advanced chronic kidney disease: a prospective, observational multi-centre vaccine surveillance study
Infections after KTx
Analysis
Infection risk after pediatric kidney transplantation, its determinants, and effects on graft function - a retrospective CERTAIN analysis
KLTX 2018
Analysis
Long-term outcome after pediatric combined liver and kidney transplantation: A CERTAIN registry analysis
Machine learning
Analysis
Machine learning to elucidate the effects of immunosuppression on graft function and multi-morbidity in paediatric kidney transplantation
Proteinuria 2016
Analysis
Proteinuria as a non-invasive marker for renal allograft histology and graft failure in paediatric renal transplant recipients
TacKidTx
Manuscript in preparation
Definition and validation of the impact of tacrolimus variability and concentration/dose ratio on allograft rejection, function and tacrolimus-related toxicity in paediatric kidney transplant recipients
DGF 2022
Ready for publication
Risk-prediction model for delayed graft function in paediatric kidney transplant recipients - an analysis based on the CERTAIN network
Upcoming research projects
Look through our upcoming research projects. If you are interested please contact the study coordinator or the CERTAIN registry HQ!
ABMR categories
Analysis plan in preparation
Precision diagnosis of ABMR categories by transcriptional profiling
DCD
Analysis plan in preparation
Donation after circulatory death
dnDSA
Analysis plan in preparation
Assessing the Long-Term Outcome of various management approaches to De Novo DSA formation with no rejection in Pediatric Kidney transplant recipients
IgA
Analysis plan in preparation
Kidney transplantation for IgA vasculitis/nephropathy or IgA nephropathy in childhood
MMF/AZA
Analysis plan in preparation
Association of immunosuppressive therapy with MMF vs. azathioprine with viremias and hospitalization rates in children during the first two years post- kidney transplant
SOPHOCLES
In preparation
StOPping Hypertension and imprOving Children's Lives after KidnEy TranSplantation