aHUS 2024
Data collection
Kidney transplantation in patients with complement-mediated/atypical hemolytic uremic syndrome (aHUS): management, outcome and risk of recurrence
New project ideas?
If you have an idea for a research topic and want to make use of the CERTAIN registry data, do not hesitate to contact us or provide us directly with a well elaborated analysis plan. Below you will find a template for an analysis plan and technical requirements.
Real-world studies?
If you are interested into real-world studies, check our for more information.
Ongoing research projects
Interested into the running project and where you can contribute? Contact the appropriate study coordinator listed below or the CERTAIN registry HQ.
AIRTrain
Recruitment
Artificial Intelligence and Biomarkers after Pediatric Renal Transplantation: Innovative Tailoring of Immunosuppression
Hypertension 2020
Data collection
Arterial hypertension and cardiovascular comorbidity after renal transplantation – triggers, treatment and sequelae.
SOPHOCLES
Recruitment
StOPping Hypertension and imprOving Children's Lives after KidnEy TranSplantation
SRNS 2019
Data collection
Recurrence of nephrotic syndrome after pediatric kidney transplantation in Europe: risk factors, treatment and outcome
Research projects under analysis
Interested into the projects where the database is already closed? Contact the appropriate study coordinator listed below or the CERTAIN registry HQ.
COVID-19
Analysis
European study on the risks of SARS-COV-2 infection in pediatric kidney transplant recipient
EuPAKT
Analysis
Prospective longitudinal multi-center study evaluating modifiable barriers to accessing transplantation and transplant outcomes in children, in Europe. Short title: European Paediatric Access to Kidney Transplantation
Steroid withdrawal
Analysis
Target trial emulation with CERTAIN data on late steroid withdrawal
Infections after KTx
Analysis
Infection risk after pediatric kidney transplantation, its determinants, and effects on graft function - a retrospective CERTAIN analysis
MMF/AZA
Analysis
Association of immunosuppressive therapy with MMF vs. azathioprine with viremias and hospitalization rates in children during the first two years post- kidney transplant
PTH 2019
Analysis
Hyperparathyroidism after paediatric renal transplantation: risk factors, management strategies and association with longitudinal growth
Vitamin D
Analysis
Association of Nutritional Vitamin D Supplementation with PTH Control, Growth, and Allograft Function in Pediatric Kidney Transplant Recipients
KLTX 2018
Manuscript in preparation
Long-term outcome after pediatric combined liver and kidney transplantation: A CERTAIN registry analysis
DGF Outcome
Manuscript in preparation
The impact of delayed graft function on rejection and long-term outcome in paediatric kidney transplant recipients - a multicentre matched case-control study
DGF 2022
Submitted to journal
Risk assessment of delayed graft function in pediatric kidney transplantation - A CERTAIN research network analysis
HPVaxResponse
Submitted to journal
Prevention of human papillomavirus (HPV) infection in paediatric kidney and liver transplant recipients and in paediatric patients with advanced chronic kidney disease: a prospective, observational multi-centre vaccine surveillance study
Failing allografts
Submitted to journal
Management of children and adolescents with failing kidney allografts – a review of current practice across Europe
Lower blood pressure
Submitted to journal
Lower cumulative blood pressure after pediatric kidney transplantation is associated with better graft function and survival: A longitudinal analysis of the CERTAIN registry
Upcoming research projects
Look through our upcoming research projects. If you are interested please contact the study coordinator or the CERTAIN registry HQ!
IgA
eCRF in preparation
Kidney transplantation for IgA vasculitis/nephropathy or IgA nephropathy in childhood
Cystinose
Analysis plan in preparation
Prospects of success and complications in patients with cystinosis after kidney transplantation
DCD
Analysis plan in preparation
Donation after circulatory death
dnDSA
Analysis plan in preparation
Assessing the long-term outcome of various management approaches to de novo DSA formation with no rejection in Pediatric Kidney transplant recipients
PTLD
Analysis plan in preparation
Risk factors for PTLD
PROM
Analysis plan in preparation
Patient-reported outcome measures in paediatric KTx
BioPTIC
Analysis plan in preparation
Biomarkers for paediatric transplantation in children
Dyslipidaemia
In preparation
Effect of dyslipidaemia on graft function and cardiovascular measures
PANDA-Kids-ATLAS
In preparation
An International, Multicentre Observational Cohort Study on Molecular Profiling of Kidney Allograft Rejection in Paediatric Transplant Recipients
Pathomechanisms
In preparation
Pathomechanisms for metabolic acidosis post-transplant – a prospective study